abstract：:Serologic testing shows that hepatitis C virus (HCV) may have a role in the pathogenesis of B-cell non-Hodgkin lymphomas (B-cell NHLs). We tried to demonstrate HCV RNA sequences in paraffin-embedded tissue from B-cell NHLs by reverse-transcription double polymerase chain reaction (RT-PCR) and Southern blotting. We stu...

journal_title：American journal of clinical pathology

authors： Karavattathayyil SJ,Kalkeri G,Liu HJ,Gaglio P,Garry RF,Krause JR,Dash S

更新日期：2000-03-01 00:00:00

abstract：:Inherited giant platelet disorders are extremely rare. The aim of this article is to review the clinical and laboratory features of this heterogeneous group and to arrive at a working classification. We conducted our literature search using the National Library of Medicine database. A total of 12 clinical entities wer...

journal_title：American journal of clinical pathology

authors： Mhawech P,Saleem A

更新日期：2000-02-01 00:00:00

abstract：:We compared the grading and staging of transurethral resection of the bladder (TURB) and cystectomy specimens for 105 patients who underwent radical cystectomy for urothelial carcinoma between 1980 and 1984. Of 105 patients, 96% underwent cystectomy within 100 days of TURB (median interval, 10 days). Grading was perfo...

journal_title：American journal of clinical pathology

authors： Cheng L,Neumann RM,Weaver AL,Cheville JC,Leibovich BC,Ramnani DM,Scherer BG,Nehra A,Zincke H,Bostwick DG

更新日期：2000-02-01 00:00:00

abstract：:Thirty drugs used primarily in critical care and hospital settings were tested in vitro to observe interference on glucose measurements with 6 hand-held glucose meters and a portable glucose analyzer. Paired differences of glucose measurements between drug-spiked samples and unspiked control samples were calculated to...

journal_title：American journal of clinical pathology

authors： Tang Z,Du X,Louie RF,Kost GJ

更新日期：2000-01-01 00:00:00

abstract：:Invasion of the visceral pleura is an important component of lung carcinoma staging, and in some studies is an independent prognostic indicator. Evaluation of invasion by H&E may be indeterminate. Elastic stains can be helpful but are performed rarely. We reviewed all lung carcinoma resections from 1993 for 13 histolo...

journal_title：American journal of clinical pathology

authors： Bunker ML,Raab SS,Landreneau RJ,Silverman JF

更新日期：1999-12-01 00:00:00

abstract：:Neoplastic transformation of epithelial cell sis commonly associated with altered synthesis of mucin glycoproteins. Few studies have been performed on the correlation between MUC 1 expression and pancreatic carcinoma using immunohistochemical methods. We compared the patterns of MUC 1 expression in normal pancreatic t...

journal_title：American journal of clinical pathology

authors： Monges GM,Mathoulin-Portier MP,Acres RB,Houvenaeghel GF,Giovannini MF,Seitz JF,Bardou VJ,Payan MJ,Olive D

更新日期：1999-11-01 00:00:00

abstract：:Telepathology is gaining acceptance as a mode of providing pathology services to remote sites, but its economic feasibility is unknown. A dynamic robotic telepathology service between the Veterans Affairs Medical Center, Iron Mountain, MI, and the Veterans Affairs Medical Center, Milwaukee, WI, provides diagnostic ser...

journal_title：American journal of clinical pathology

authors： Agha Z,Weinstein RS,Dunn BE

更新日期：1999-10-01 00:00:00

abstract：:Acute toxic hepatic necrosis is common and may be fatal. Predicting clinical outcome may be aided by following serum markers that could indicate recovery or may signify massive (substantial) destruction of functional liver mass. Previously, in a published case of chloroform poisoning, we serially assayed serum biomark...

journal_title：American journal of clinical pathology

authors： Horn KD,Wax P,Schneider SM,Martin TG,Nine JS,Moraca MA,Virji MA,Aronica PA,Rao KN

更新日期：1999-09-01 00:00:00

abstract：:In lung transplant recipients, bronchoalveolar lavage (BAL) is mainly performed to detect infectious agents. However, in addition to microorganisms, epithelial cell atypia may be identified, and determination of its significance is necessary. Specimens obtained at BAL in lung and heart-lung transplant recipients (LTRs...

journal_title：American journal of clinical pathology

authors： Ohori NP

更新日期：1999-08-01 00:00:00

abstract：:Chronic myeloproliferative diseases (MPDs) are not associated with consistent cytogenetic or molecular abnormalities. Demonstration of clonal cell growth by analysis of X-chromosome inactivation (XCI) patterns in females provides a promising tool for diagnosis. However, this technique can be complicated by excessive l...

journal_title：American journal of clinical pathology

authors： Mitterbauer G,Winkler K,Gisslinger H,Geissler K,Lechner K,Mannhalter C

更新日期：1999-07-01 00:00:00

abstract：:The cell cycle consists of an initial growth phase (G1), DNA replication (S), a gap phase (G2), and mitosis (M), after which the cell may differentiate or enter the resting state (G0). The cycle is driven by a number of positive and negative regulatory phosphorylation and dephosphorylation events, involving protein ki...

journal_title：American journal of clinical pathology

authors： Dictor M,Ehinger M,Mertens F,Akervall J,Wennerberg J

更新日期：1999-07-01 00:00:00

abstract：:We compared the differential counts of normal and abnormal bone marrow from touch imprints with those from aspirate smears to determine whether the touch imprint was reliable for independent routine use in the examination of bone marrow and the classification of hematologic abnormalities. Normocellular bone marrow spe...

journal_title：American journal of clinical pathology

authors： Aboul-Nasr R,Estey EH,Kantarjian HM,Freireich EJ,Andreeff M,Johnson BJ,Albitar M

更新日期：1999-06-01 00:00:00

abstract：:Primary thymic epithelial neoplasms have been the subject of much controversy in recent years owing to the difficulties posed by these tumors for precise histopathologic typing and prognostication. A number of classification schemes using different terminology have been proposed, none of which has satisfactorily manag...

journal_title：American journal of clinical pathology

authors： Suster S,Moran CA

更新日期：1999-06-01 00:00:00

abstract：:Although cytology laboratories are mandated to rescreen at least 10% of cervicovaginal smears, there is no uniform national rescreening practice. Follow-up data for 16,188 rescreened cervicovaginal smears were studied and decision analysis was performed to determine an optimal rescreening strategy. High-grade dysplasi...

journal_title：American journal of clinical pathology

authors： Raab SS,Bishop NS,Zaleski MS

更新日期：1999-05-01 00:00:00

abstract：:The examination of T-cell receptor (TCR) repertoires has an important role in the study of lymphoproliferative disorders and autoimmune diseases. Analysis of the complementarity-determining region 3 (CDR3) of the TCR beta chain is used to assess the clonality of T-cell populations. We developed a rapid fluorescence-ba...

journal_title：American journal of clinical pathology

authors： Lue C,Mitani Y,Crew MD,George JF,Fink LM,Schichman SA

更新日期：1999-05-01 00:00:00

abstract：:The standard method for detecting antinuclear antibodies (ANAs) is by immunofluorescence assay (IFA), a method that is labor intensive and subjective. In an attempt to overcome these limitations, several commercial enzyme immunoassays (EIAs) have been developed. We report the results of our evaluation of the ANA Micro...

journal_title：American journal of clinical pathology

authors： Reisner BS,DiBlasi J,Goel N

更新日期：1999-04-01 00:00:00

abstract：:We noticed almost routine disparate results in margin lengths when colorectal specimens are measured in vivo by the surgeon and in vitro by the pathologist. We studied 26 sigmoid and rectum specimens to document the amount of organ shrinkage after surgical removal and fixation. Each specimen had a 5.0-cm segment at ea...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Soman A,Sacksner J

更新日期：1999-03-01 00:00:00

abstract：:The effect of changes in cytology laboratory costs, including the costs of new technologies, on the cost-effectiveness of cervical cancer prevention has not been studied. Using University of Iowa laboratory detection rates and costs, a decision model determined the cost-effectiveness of the laboratory with and without...

journal_title：American journal of clinical pathology

authors： Raab SS,Zaleski MS,Silverman JF

更新日期：1999-02-01 00:00:00

abstract：:We surveyed 271 laboratories participating in a quality assessment program to ascertain whether the use of a calibration curve for determining the international normalized ratio (INR) would improve interlaboratory accuracy and precision. Lyophilized warfarinized samples with INR values assigned through manual calibrat...

journal_title：American journal of clinical pathology

authors： Brien WF,Baskerville JC,Taberner DA,Crawford L

更新日期：1999-02-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) is clinically and pathologically heterogeneous, leading to some difficulty in its diagnosis and acceptance as a specific entity. ALCL can be subdivided into different groups according to histologic features (pleomorphic, monomorphic, small cell predominant, Hodgkin's disease-relat...

journal_title：American journal of clinical pathology

authors： Kinney MC,Kadin ME

更新日期：1999-01-01 00:00:00

abstract：:The clonality of dendritic cell proliferations arising in patients with previously diagnosed B-cell non-Hodgkin lymphoma has not been determined. The highly polymorphic human androgen receptor gene (HUMARA) can be used to assess the pattern of X-chromosome inactivation and, hence, the clonality of tumors in female pat...

journal_title：American journal of clinical pathology

authors： Wu CD,Wickert RS,Williamson JE,Sun NC,Brynes RK,Chan WC

更新日期：1999-01-01 00:00:00

abstract：:Trends in surgical practice suggest that pathologists will encounter increased numbers of patients with small invasive ductal adenocarcinomas; small, if any, metastatic deposits in axillary lymph nodes (ALNs); and possibly fewer ALN specimens to examine. New prognostic histologic features may be needed in this environ...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Mani A,Vicini F,Ingold J

更新日期：1999-01-01 00:00:00

abstract：:Complete hydatidiform moles (CHM) and partial hydatidiform moles (PHM) represent different clinicopathologic entities. To obtain prognostic and therapeutic information about both entities, it is important that pathologic classification be as accurate as possible. The distinction of molar pregnancy and an abortus with ...

journal_title：American journal of clinical pathology

authors： Ostrzega N,Phillipson J,Liu P

更新日期：1998-12-01 00:00:00

abstract：:Immunohistochemistry occasionally is used to determine the lineage of entirely necrotic tumors. However, the sensitivity and specificity of antibodies on necrotic tissue are unknown. To determine the usefulness of immunohistochemistry with necrotic lesions, a series of 24 known tumors consisting of 14 carcinomas, 2 ly...

journal_title：American journal of clinical pathology

authors： Judkins AR,Montone KT,LiVolsi VA,van de Rijn M

更新日期：1998-11-01 00:00:00

abstract：:Adenocarcinomas expressing gastric mucins often are accompanied by ectopic gastric mucosa or pyloric metaplasia. We have previously described mucinous bronchioloalveolar carcinoma (mucinous BAC) producing gastric mucins. In the lung tissue, mucous cells seemingly similar to gastric mucous cells are present in congenit...

journal_title：American journal of clinical pathology

authors： Ota H,Langston C,Honda T,Katsuyama T,Genta RM

更新日期：1998-10-01 00:00:00

abstract：:Recent studies in Western populations have shown that trisomy 3 is the most frequent chromosomal abnormality in primary gastric lymphoma (PGL). To study the incidence of trisomy 3 and its implications for the pathogenesis of PGL in Hong Kong, we have applied the technique of chromosome in situ hybridization in 13 case...

journal_title：American journal of clinical pathology

authors： Zhang Y,Cheung AN,Chan AC,Shen DH,Xu WS,Chung LP,Ho FC

更新日期：1998-09-01 00:00:00

abstract：:To determine the current frequency of discovering important diagnoses at autopsy, the diagnoses made in all complete or "no head" autopsies during 1994 at a major tertiary care transplantation referral center were retrospectively compared with the diagnoses made antemortem. Of 176 autopsies, 79 (44.9%) revealed 1 or m...

journal_title：American journal of clinical pathology

authors： Nichols L,Aronica P,Babe C

更新日期：1998-08-01 00:00:00

abstract：:We sought to determine the sensitivity and specificity of immunohistochemistry using the TORDJI-22 MoAb (BioGenex, San Ramon, Calif), which is specific for the C-100 protein of the hepatitis C virus, compared with reverse transcriptase-polymerase chain reaction (RT-PCR) of tissue for viral RNA. RT-PCR had been perform...

journal_title：American journal of clinical pathology

authors： Brody RI,Eng S,Melamed J,Mizrachi H,Schneider RJ,Tobias H,Teperman LW,Theise ND

更新日期：1998-07-01 00:00:00

abstract：:Cervical cone biopsy has become an important surgical procedure for endocervical adenocarcinoma in situ (AIS), especially for patients who desire to retain their fertility. Establishing the usefulness of the endocervical margin status in cone biopsy specimens as a predictor of residual AIS is paramount. We examined th...

journal_title：American journal of clinical pathology

authors： Goldstein NS,Mani A

更新日期：1998-06-01 00:00:00

abstract：:Percent-free prostate-specific antigen (proportion of free prostate-specific antigen [PSA] to total PSA) has been shown recently in studies on frozen serum samples to be more useful than total PSA alone in distinguishing prostate cancer from benign conditions of the prostate gland. The primary purpose of our study was...

journal_title：American journal of clinical pathology

authors： Henricks WH,England BG,Giacherio DA,Oesterling JE,Wojno KJ

更新日期：1998-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection may be complicated by non-Hodgkin's lymphoma. We describe eight cases of B-cell extranodal non-Hodgkin's lymphoma occurring during the course of chronic HCV-related hepatic disease (low-grade of mucosa-associated lymphoid tissue [MALT]-type; diffuse large cell; Burkitt; diffuse small ...

journal_title：American journal of clinical pathology

authors： Ascoli V,Lo Coco F,Artini M,Levrero M,Martelli M,Negro F

更新日期：1998-05-01 00:00:00

abstract：:Tumors and pseudotumors of the liver account for fewer than 2% of the tumors in children and vary considerably in incidence throughout the pediatric age range, with hepatoblastoma, infantile hemangioendothelioma, and mesenchymal hamartoma seen most frequently in the first 2 years of life and hepatocellular carcinoma, ...

journal_title：American journal of clinical pathology

authors： Stocker JT

更新日期：1998-04-01 00:00:00

abstract：:Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...

journal_title：American journal of clinical pathology

authors： Akhtar MS,Blair AJ,King TC,Sweeney JD

更新日期：1998-04-01 00:00:00

abstract：:The expression of the cell-cycle-associated Ki-67 antigen by MIB-1 monoclonal antibody was retrospectively assessed in 35 surgically resected neuroendocrine tumor specimens of the pancreas embedded in paraffin. The MIB-1 proliferation index was correlated with the classification of the neuroendocrine tumors of the pan...

journal_title：American journal of clinical pathology

authors： Gentil Perret A,Mosnier JF,Buono JP,Berthelot P,Chipponi J,Balique JG,Cuilleret J,Dechelotte P,Boucheron S

更新日期：1998-03-01 00:00:00

abstract：:One of the functions of von Willebrand factor (vWF) is to serve as a carrier of clotting factor VIII (FVIII). Deficiency of this function results in the von Willebrand disease (vWD) variant type 2N, which resembles hemophilia A. We describe a new sandwich enzyme-linked immunosorbent assay (ELISA) to study the ability ...

journal_title：American journal of clinical pathology

authors： Casonato A,Pontara E,Zerbinati P,Zucchetto A,Girolami A

更新日期：1998-03-01 00:00:00

abstract：:Although reports have suggested the incomplete type of intestinal metaplasia (IM) had a close correlation with carcinoma, considerable data showed no apparent relationship between the particular type of IM and the intestinal type carcinoma. The purpose of this study was to establish a novel classification of IM using ...

journal_title：American journal of clinical pathology

authors： Matsuzaki H,Shimada S,Uno K,Tsuruta J,Ogawa M

更新日期：1998-02-01 00:00:00

abstract：:Proliferative activity in astrocytomas, measured by image cytometry, was related to prognosis. Fifty-eight astrocytic neoplasms (grade 1 or 2, 11; grade 3, 31; glioblastoma multiforme, 16) were immunostained for Ki-67 (MIB-1; 1:50) and proliferating cell nuclear antigen (PCNA; prediluted). Proliferative activity (nucl...

journal_title：American journal of clinical pathology

authors： Kirkegaard LJ,DeRose PB,Yao B,Cohen C

更新日期：1998-01-01 00:00:00

abstract：:We evaluated the performance (ie, imprecision, inaccuracy, and analytic sensitivity) of the Sysmex SE-9000 commercial hematology analyzer (TOA Medical Electronics, Kobe, Japan) on differential leukocyte counts according to the National Committee for Clinical Laboratory Standards H20-A protocol. The results obtained we...

journal_title：American journal of clinical pathology

authors： Buttarello M,Bulian P,Temporin V,Rizzotti P

更新日期：1997-12-01 00:00:00

abstract：:To assess the usefulness of the cytocentrifuge Gram stain as a urine screening test in the clinical microbiology laboratory for the elimination of culture for screen-negative specimens, we compared the results of the cytocentrifuge Gram stain to the results of culture for 1,171 urine specimens. The data were analyzed ...

journal_title：American journal of clinical pathology

authors： Winquist AG,Orrico MA,Peterson LR

更新日期：1997-11-01 00:00:00

abstract：:A 61-year-old man with acquired immunodeficiency syndrome (AIDS) sought care because of the onset of progressive dysphagia. He was found to have a perforated, fungating esophageal mass. The combined histologic and immunologic findings were diagnostic of Hodgkin's disease, nodular sclerosis type, lymphocyte-depleted va...

journal_title：American journal of clinical pathology

authors： Gelb AB,Medeiros LJ,Chen YY,Weiss LM,Weidner N

更新日期：1997-11-01 00:00:00